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HM-cytosine

Catalog No. T35363 CAS 1123-95-1

Synonyms: 5hmC, 5-Hydroxymethylcytosine

HM-cytosine (5hmC) is a naturally occurring component of mammalian genomic DNA and is thought to be the sixth base of DNA [1]. HM-cytosine is an intermediate metabolite for demethylation of active DNA [2]. HM-cytosine is an ep

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HM-cytosine, CAS 1123-95-1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 40.00
2 mg	In stock	$ 57.00
5 mg	In stock	$ 94.00
10 mg	In stock	$ 147.00
25 mg	In stock	$ 289.00
50 mg	In stock	$ 429.00
100 mg	In stock	$ 622.00
1 mL * 10 mM (in DMSO)	In stock	$ 77.00

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Purity: 99.49%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	5hmC, 5-Hydroxymethylcytosine
Molecular Weight	141.13
Formula	C5H7N3O2
CAS No.	1123-95-1

Storage

store at low temperature,keep away from direct sunlight,store under nitrogen

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 5 mg/mL (35.43 mM)

References and Literature

1. Ke Fang, et al. [Advances on the profiling of 5-hydroxymethylcytosine]. Yi Chuan. 2016 Mar;38(3):206-16. 2. Jesús Rafael Rodríguez-Aguilera, et al. Genome-wide 5-hydroxymethylcytosine (5hmC) emerges at early stage of in vitro differentiation of a putative hepatocyte progenitor. Sci Rep. 2020 May 8;10(1):7822. 3. Wenshuai Li, et al. 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers. Cell Res. 2017 Oct;27(10):1243-1257.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compounds Library Max Bioactive Compound Library Mouse Metabolite Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

HM-cytosine 1123-95-1 Others 5hmC 5 Hydroxymethylcytosine 5Hydroxymethylcytosine 5-Hydroxymethylcytosine inhibitor inhibit

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