Shopping Cart

Remove All
Your shopping cart is currently empty

HM-cytosine

Name: HM-cytosine
Brand: TargetMol
SKU: T35363
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T35363Cas No. 1123-95-1

Alias 5-Hydroxymethylcytosine, 5hmC

HM-cytosine (5hmC) is a naturally occurring component of mammalian genomic DNA and is thought to be the sixth base of DNA [1]. HM-cytosine is an intermediate metabolite for demethylation of active DNA [2]. HM-cytosine is an ep

HM-cytosine

🥰Excellent

Purity: 99.49%

Catalog No. T35363Alias 5-Hydroxymethylcytosine, 5hmCCas No. 1123-95-1

Pack Size	Price	Availability
1 mg	$40	In Stock
2 mg	$57	In Stock
5 mg	$94	In Stock
10 mg	$147	In Stock
25 mg	$289	In Stock
50 mg	$429	In Stock
100 mg	$622	In Stock
1 mL x 10 mM (in DMSO)	$77	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.49%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	HM-cytosine (5hmC) is a naturally occurring component of mammalian genomic DNA and is thought to be the sixth base of DNA [1]. HM-cytosine is an intermediate metabolite for demethylation of active DNA [2]. HM-cytosine is an ep
Synonyms	5-Hydroxymethylcytosine, 5hmC

Chemical Properties

Molecular Weight	141.13
Formula	C₅H₇N₃O₂
Cas No.	1123-95-1
Smiles	NC1=C(CO)C=NC(O)=N1
Relative Density.	1.3818 g/cm3 (Estimated)

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 5 mg/mL (35.43 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.0857 mL	35.4283 mL	70.8567 mL	354.2833 mL
5 mM	1.4171 mL	7.0857 mL	14.1713 mL	70.8567 mL
10 mM	0.7086 mL	3.5428 mL	7.0857 mL	35.4283 mL
20 mM	0.3543 mL	1.7714 mL	3.5428 mL	17.7142 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc