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HM-cytosine

Catalog No. T35363   CAS 1123-95-1
Synonyms: 5hmC, 5-Hydroxymethylcytosine

HM-cytosine (5hmC) is a naturally occurring component of mammalian genomic DNA and is thought to be the sixth base of DNA [1]. HM-cytosine is an intermediate metabolite for demethylation of active DNA [2]. HM-cytosine is an ep

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HM-cytosine Chemical Structure
HM-cytosine, CAS 1123-95-1
Pack Size Availability Price/USD Quantity
1 mg In stock $ 40.00
2 mg In stock $ 57.00
5 mg In stock $ 94.00
10 mg In stock $ 147.00
25 mg In stock $ 289.00
50 mg In stock $ 429.00
100 mg In stock $ 622.00
1 mL * 10 mM (in DMSO) In stock $ 77.00
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Purity: 99.49%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description HM-cytosine (5hmC) is a naturally occurring component of mammalian genomic DNA and is thought to be the sixth base of DNA [1]. HM-cytosine is an intermediate metabolite for demethylation of active DNA [2]. HM-cytosine is an ep
Synonyms 5hmC, 5-Hydroxymethylcytosine
Molecular Weight 141.13
Formula C5H7N3O2
CAS No. 1123-95-1

Storage

store at low temperture,keep away from direct sunlight,store under nitrogen

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 5 mg/mL (35.43 mM)

TargetMolReferences and Literature

1. Ke Fang, et al. [Advances on the profiling of 5-hydroxymethylcytosine]. Yi Chuan. 2016 Mar;38(3):206-16. 2. Jesús Rafael Rodríguez-Aguilera, et al. Genome-wide 5-hydroxymethylcytosine (5hmC) emerges at early stage of in vitro differentiation of a putative hepatocyte progenitor. Sci Rep. 2020 May 8;10(1):7822. 3. Wenshuai Li, et al. 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers. Cell Res. 2017 Oct;27(10):1243-1257.

Related compound libraries

This product is contained In the following compound libraries:
Bioactive Compound Library Bioactive Compounds Library Max Mouse Metabolite Compound Library

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Keywords

HM-cytosine 1123-95-1 Others 5hmC 5 Hydroxymethylcytosine 5Hydroxymethylcytosine 5-Hydroxymethylcytosine inhibitor inhibit

 

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