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Betulinaldehyde
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Catalog No. T3796Cas No. 13159-28-9
Alias Betunal, Betulinic aldehyde, Betulinal
Betulinaldehyde (Betunal) has the inhibition of Saccharomyces sp and alpha-glucosidase. Betulinaldehyde induces apoptosis in mouse B16 2F2 cells. Betulinaldehyde has anti-proliferative activity against mouse +SA mammary epithelial cells.
Betulinaldehyde
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Purity: 99.11%
Catalog No. T3796Alias Betunal, Betulinic aldehyde, BetulinalCas No. 13159-28-9
Betulinaldehyde (Betunal) has the inhibition of Saccharomyces sp and alpha-glucosidase. Betulinaldehyde induces apoptosis in mouse B16 2F2 cells. Betulinaldehyde has anti-proliferative activity against mouse +SA mammary epithelial cells.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $35 | In Stock | In Stock | |
| 25 mg | $67 | In Stock | In Stock | |
| 50 mg | $95 | In Stock | In Stock | |
| 100 mg | $138 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.11%
Color:White
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Product Introduction
Betulinaldehyde AI Summary
Betulinaldehyde exhibits a range of biological activities including antiproliferative, melanogenic, antiparasitic, antiviral, antimycobacterial, and enzyme inhibitory effects. It shows antiproliferative activity against mouse +SA mammary epithelial cells with an IC50 of 19400.0 nM after 4 days. It induces melanogenesis in mouse B16 2F2 cells with an ED50 of 3.3 μM and inhibits the growth of these cells with an IC50 of 6400.0 nM. At 10 μM, it induces apoptosis in these cells with a 70.4% activity rate. Against Leishmania amazonensis, it exhibits antiparasitic activity at 136 μM and 68 μM, with survival indices of 12.0% and 42.0%, respectively, while also showing toxicity to peritoneal macrophages at these concentrations, with survival induction rates of 70.0% and 80.0%. It shows antiviral activity against SFV infected in BHK cells, reducing the surviving virus fraction to 1.0% at 50 μM after 14 hours, and exhibits no cytotoxicity against human HuH7 cells at the same concentration over 24 hours. The compound has antimycobacterial activity against Mycobacterium tuberculosis H37Rv with a MIC value greater than 90 at 25.0 mg/ml. Additionally, it inhibits human CD73 activity with an IC50 greater than 100,000.0 nM, assessed via a malachite green reagent-based colorimetric assay measuring inorganic phosphate release after substrate hydrolysis..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Betulinaldehyde (Betunal) has the inhibition of Saccharomyces sp and alpha-glucosidase. Betulinaldehyde induces apoptosis in mouse B16 2F2 cells. Betulinaldehyde has anti-proliferative activity against mouse +SA mammary epithelial cells. |
| Synonyms | Betunal, Betulinic aldehyde, Betulinal |
| Molecular Weight | 440.7 |
| Formula | C30H48O2 |
| Cas No. | 13159-28-9 |
| Smiles | [H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C=O)C(C)=C |
| Relative Density. | 1.041g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | Chloroform, Dichloromethane, Ethyl Acetate, Acetone: Soluble DMSO: 1 mg/mL (2.27 mM), Sonication is recommended.  | ||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (2.27 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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