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Orticumab (Synonyms: MLDL1278A)
Catalog No. T77123 Copy Product Info
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Orticumab (MLDL1278A) is a recombinant human monoclonal antibody engineered to specifically bind to epitopes on oxidized low-density lipoprotein (oxLDL). it demonstrates therapeutic potential by modulating autoimmune responses against oxLDL, thereby improving atherosclerotic plaque pathology, and also shows significant promise for the treatment of autoimmune inflammatory conditions such as psoriasis.
Orticumab
Copy Product Info🥰Excellent
Catalog No. T77123
Synonyms MLDL1278A
Orticumab (MLDL1278A) is a recombinant human monoclonal antibody engineered to specifically bind to epitopes on oxidized low-density lipoprotein (oxLDL). it demonstrates therapeutic potential by modulating autoimmune responses against oxLDL, thereby improving atherosclerotic plaque pathology, and also shows significant promise for the treatment of autoimmune inflammatory conditions such as psoriasis.
Orticumab
Cas No. 1314241-10-5
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $413 | - | In Stock | |
| 5 mg | $1,230 | - | In Stock | |
| 10 mg | $1,990 | - | In Stock | |
| 25 mg | $2,950 | - | In Stock | |
| 50 mg | $3,980 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:≥95% (SDS-PAGE); 98.56% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Orticumab (MLDL1278A) is a recombinant human monoclonal antibody engineered to specifically bind to epitopes on oxidized low-density lipoprotein (oxLDL). it demonstrates therapeutic potential by modulating autoimmune responses against oxLDL, thereby improving atherosclerotic plaque pathology, and also shows significant promise for the treatment of autoimmune inflammatory conditions such as psoriasis. |
| In vivo | Methods: Orticumab (10 mg/kg, intraperitoneal injection, once a week for three weeks) was used to treat B6.lpr.ApoE-/- mice (18 weeks old) fed a high-fat diet (HFD) and its therapeutic effect was observed. Results: Orticumab treatment reduced aortic arch atherosclerosis by 42.8% and CD68 macrophage subvalvular plaque staining by 30.5%. [1] |
| Synonyms | MLDL1278A |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | oxLDL |
| Molecular Weight | ~150 kDa |
| Cas No. | 1314241-10-5 |
| Isotype | Human IgG1 lambda2 |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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