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W1131 TFA is a potent STAT3 inhibitor inducing ferroptosis and effectively halting cancer progression in subcutaneous xenograft, organoid, and PDX models of gastric cancer. It mitigates chemoresistance to 5-FU in cancer cells and modulates the cell cycle, DNA damage response, and oxidative phosphorylation, targeting pathways such as IL6-JAK-STAT3 and ferroptosis [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $100 | In Stock | |
5 mg | $247 | In Stock | |
10 mg | $396 | In Stock | |
25 mg | $795 | In Stock | |
50 mg | $1,280 | In Stock | |
100 mg | $1,980 | In Stock | |
200 mg | $2,770 | In Stock |
Description | W1131 TFA is a potent STAT3 inhibitor inducing ferroptosis and effectively halting cancer progression in subcutaneous xenograft, organoid, and PDX models of gastric cancer. It mitigates chemoresistance to 5-FU in cancer cells and modulates the cell cycle, DNA damage response, and oxidative phosphorylation, targeting pathways such as IL6-JAK-STAT3 and ferroptosis [1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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