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Drotrecogin alfa (activated)
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Catalog No. T82526 Copy Product Info
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Drotrecogin alfa (activated) (DrotAA), a recombinant human activated protein C (APC), mitigates smoke-induced elevations in pulmonary microvascular permeability and proinflammatory cytokine IL-1β levels in rats. It also inhibits coagulation and inflammation while enhancing fibrinolysis. Drotrecogin alfa (activated) is applicable in severe sepsis research [1] [2].
Drotrecogin alfa
(activated)
Cas No. 98530-76-8
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Drotrecogin alfa (activated) (DrotAA), a recombinant human activated protein C (APC), mitigates smoke-induced elevations in pulmonary microvascular permeability and proinflammatory cytokine IL-1β levels in rats. It also inhibits coagulation and inflammation while enhancing fibrinolysis. Drotrecogin alfa (activated) is applicable in severe sepsis research [1] [2]. |
| In vivo | Drotrecogin alfa (activated) administered intravenously at doses up to 20 mg/kg immediately post smoke exposure markedly reduces smoke inhalation injury in a dose-dependent fashion within 2 hours following the event. At a dose of 20 mg/kg, Drotrecogin alfa (activated) enhances the expiratory phase of pulmonary dynamic compliance [2]. |
| Cas No. | 98530-76-8 |
| Storage | -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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