FGFR1 inhibitor-2

Name: FGFR1 inhibitor-2
Brand: TargetMol
SKU: T39992
Rating: 4.5 (1 reviews)

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Catalog No. T39992Cas No. 2410612-08-5

Alias FGFR1 inhibitor-2

FGFR1 inhibitor-2 (with an IC50 of 4.55 μM in MDA-MB-231 cells) is a potent inhibitor of FGFR1. It is specifically useful for studying metastatic triple-negative breast cancer.

FGFR1 inhibitor-2

😃Good

Catalog No. T39992Alias FGFR1 inhibitor-2Cas No. 2410612-08-5

FGFR1 inhibitor-2 (with an IC50 of 4.55 μM in MDA-MB-231 cells) is a potent inhibitor of FGFR1. It is specifically useful for studying metastatic triple-negative breast cancer.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
5 mg	$970	Inquiry	Inquiry

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Product Introduction

Bioactivity

Description	FGFR1 inhibitor-2 (with an IC50 of 4.55 μM in MDA-MB-231 cells) is a potent inhibitor of FGFR1. It is specifically useful for studying metastatic triple-negative breast cancer.
In vitro	FGFR1 inhibitor-2, when applied at concentrations of 3 and 6 μM to MDA-MB-231 cells for a duration of 48 hours, effectively diminishes FGFR1 expression, as evidenced by Western Blot Analysis[1]. Additionally, a dose-dependent increase in the apoptotic index of MDA-MB-231 cells is observed, reaching a significant 10.6-fold elevation at a concentration of 5 μM, indicating a pronounced pro-apoptotic effect at this dosage[1].
Synonyms	FGFR1 inhibitor-2

Chemical Properties

Molecular Weight	507.461
Formula	C₂₅H₂₂F₅N₃O₃
Cas No.	2410612-08-5
Relative Density.	1.350 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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