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Glycyrrhizic acid

Name: Glycyrrhizic acid
Brand: TargetMol
SKU: T2741
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2741Cas No. 1405-86-3

Alias Glycyrrhizin

Glycyrrhizic acid (Glycyrrhizin) is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.

Glycyrrhizic acid

🥰Excellent

Purity: 99.49%

Catalog No. T2741Alias GlycyrrhizinCas No. 1405-86-3

Glycyrrhizic acid (Glycyrrhizin) is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.

Pack Size	Price	Availability
25 mg	$30	In Stock
50 mg	$42	In Stock
100 mg	$68	In Stock
500 mg	$198	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock

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Batch Information

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Purity:99.49%

Resource Download

COA LCMS HNMR HPLC

Product Introduction

Bioactivity

Description	Glycyrrhizic acid (Glycyrrhizin) is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.
Targets&IC50	MAO:0.16 μM, HEK293 cells:0.015 μM, Hepatocyte cells:82.4 μM, ECV-304 cells:> 119 μM, MDCK cells:39.6 μM, Raji cells:381 μM
Alias	Glycyrrhizin

Chemical Properties

Molecular Weight	822.93
Formula	C₄₂H₆₂O₁₆
Cas No.	1405-86-3
Smiles	[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](O[C@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)C(O)=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O
Relative Density.	1.1442 g/cm3 (Estimated)

Storage & Solubility Information

Storage

store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: 93 mg/mL (113.01 mM), Sonication is recommended.

DMSO: 93 mg/mL (113.01 mM), Sonication is recommended.

In Vivo Formulation

5% DMSO+95% Saline: 4.65 mg/mL (5.65 mM), Solution.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2152 mL	6.0759 mL	12.1517 mL	60.7585 mL
5 mM	0.2430 mL	1.2152 mL	2.4303 mL	12.1517 mL
10 mM	0.1215 mL	0.6076 mL	1.2152 mL	6.0759 mL
20 mM	0.0608 mL	0.3038 mL	0.6076 mL	3.0379 mL
50 mM	0.0243 mL	0.1215 mL	0.2430 mL	1.2152 mL
100 mM	0.0122 mL	0.0608 mL	0.1215 mL	0.6076 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc