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Anti-B4GALT1 Antibody (2T352) is a Mouse antibody targeting B4GALT1. Anti-B4GALT1 Antibody (2T352) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-B4GALT1 Antibody (2T352) is a Mouse antibody targeting B4GALT1. Anti-B4GALT1 Antibody (2T352) can be used in ELISA. |
Alias | β4Gal-T1, β-1,4-GalT1, β-1,4-GalT, UDP-Gal:βGlcNAc β 1,4- galactosyltransferase, polypeptide 1, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, Ggtb2, Ggtb, GalT, beta4Gal-T1, beta-1,4-GalT1, beta-1,4-GalT, b4Gal-T1, B-1,4-GalT1, B-1,4-GalT |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 2T352 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human B4GALT1 (rh B4GALT1; TMPY-01291; NP_001488.2; Gly 44-Ser 398). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Beta1,4-Galactosyltransferase-I (B4GALT1), one of seven beta1,4-galactosyltransferases, is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. They have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. B4GALT1 gene directs production of B4GALT1 protein using either of two transcription start sites. The product of the smaller transcript serves the traditional biosynthetic role in the Golgi. This form also complexes with α-lactalbumin, a mammary-specific protein, to form lactose synthase. In addition to a biosynthetic role, the protein translated from the longer transcript appears on the plasma membranes of some cells where it serves as a signalling receptor in cell-matrix interactions such as sperm-egg binding. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human B4GALT1 protein (TMPY-01291) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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