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SB 328437

Name: SB 328437
Brand: TargetMol
SKU: T23321
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T23321Cas No. 247580-43-4

Alias ZINC29222893, (S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate

SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).

SB 328437

🥰Excellent

Purity: 99.54%

Catalog No. T23321Alias ZINC29222893, (S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoateCas No. 247580-43-4

SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$35	In Stock	In Stock
5 mg	$79	In Stock	In Stock
10 mg	$132	In Stock	In Stock
25 mg	$278	In Stock	In Stock
50 mg	$438	In Stock	In Stock
100 mg	$687	-	In Stock
200 mg	$972	-	In Stock
1 mL x 10 mM (in DMSO)	$66	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.54%

Resource Download

COA HNMR

Product Introduction

Bioactivity

Description	SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).
Targets&IC50	CCR3:4.5 nM (IC50)
Synonyms	ZINC29222893, (S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate

Chemical Properties

Molecular Weight	378.38
Formula	C₂₁H₁₈N₂O₅
Cas No.	247580-43-4
Smiles	COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Relative Density.	1.305 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (264.3 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6428 mL	13.2142 mL	26.4285 mL	132.1423 mL
5 mM	0.5286 mL	2.6428 mL	5.2857 mL	26.4285 mL
10 mM	0.2643 mL	1.3214 mL	2.6428 mL	13.2142 mL
20 mM	0.1321 mL	0.6607 mL	1.3214 mL	6.6071 mL
50 mM	0.0529 mL	0.2643 mL	0.5286 mL	2.6428 mL
100 mM	0.0264 mL	0.1321 mL	0.2643 mL	1.3214 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc