Shopping Cart

Your shopping cart is currently empty

AZD8329

Name: AZD8329
Brand: TargetMol
SKU: T14383
Price: 84 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T14383Cas No. 1048668-70-7

Alias AZD-8329, AZD 8329

AZD8329 is a selective and potent 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor that inhibits 11β-HSD2, 17β-HSD1, 17β-HSD3, and can be used for the study of allergic reactions in humans.

AZD8329

🥰Excellent

Purity: 99.31%

Catalog No. T14383Alias AZD-8329, AZD 8329Cas No. 1048668-70-7

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$84	-	In Stock
5 mg	$198	-	In Stock
10 mg	$328	-	In Stock
25 mg	$679	-	In Stock
50 mg	$996	-	In Stock
100 mg	$1,730	-	In Stock
1 mL x 10 mM (in DMSO)	$226	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

Questions

Batch Information

Select Batch

Purity:99.31%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	AZD8329 is a selective and potent 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor that inhibits 11β-HSD2, 17β-HSD1, 17β-HSD3, and can be used for the study of allergic reactions in humans.
Targets&IC50	11β-HSD1 (human):9 nM
In vitro	AZD8329 has IC50 values ranging from 0.009 to 6.1 μM for enzymes from different species and human adipocytes [1].
Synonyms	AZD-8329, AZD 8329

Chemical Properties

Molecular Weight	421.53
Formula	C₂₅H₃₁N₃O₃
Cas No.	1048668-70-7
Smiles	CC(C)(C)c1c(cnn1-c1ccc(cc1)C(O)=O)C(=O)NC1C2CC3CC(C2)CC1C3
Relative Density.	1.37 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (118.62 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.74 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3723 mL	11.8616 mL	23.7231 mL	118.6155 mL
5 mM	0.4745 mL	2.3723 mL	4.7446 mL	23.7231 mL
10 mM	0.2372 mL	1.1862 mL	2.3723 mL	11.8616 mL
20 mM	0.1186 mL	0.5931 mL	1.1862 mL	5.9308 mL
50 mM	0.0474 mL	0.2372 mL	0.4745 mL	2.3723 mL
100 mM	0.0237 mL	0.1186 mL	0.2372 mL	1.1862 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc