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Anti-CXCL13/BCA-1 Antibody (6I514)
🥰Excellent
Catalog No. TMAY-03664
Anti-CXCL13/BCA-1 Antibody (6I514) is a Mouse antibody targeting CXCL13/BCA-1. Anti-CXCL13/BCA-1 Antibody (6I514) can be used in ELISA.
Anti-CXCL13/BCA-1 Antibody (6I514)
Anti-CXCL13/BCA-1 Antibody (6I514)
🥰Excellent
Catalog No. TMAY-03664
Anti-CXCL13/BCA-1 Antibody (6I514) is a Mouse antibody targeting CXCL13/BCA-1. Anti-CXCL13/BCA-1 Antibody (6I514) can be used in ELISA.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CXCL13/BCA-1 Antibody (6I514) is a Mouse antibody targeting CXCL13/BCA-1. Anti-CXCL13/BCA-1 Antibody (6I514) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 6I514 |
| Reactivity | Canine |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Canine BCA-1 / CXCL13 ( TMPY-03708; XP_851619.3; Val23-Asn110). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The chemokine CXCL13, also known as BCA-1 (B-cell-attracting chemokine-1) or BLC (B-lymphocyte chemoattractant), which belongs to the CXC chemokine family. CXCL13 and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues. CXCL13 is known to dictate homing and motility of B cells in lymphoid tissue and has been implicated in the formation of ectopic lymphoid tissue in chronic inflammation. It involves in B-cell compartmental homing within secondary lymphoid organs and recently implicated in the pathogenesis of inflammatory and malignant lymphocyte-mediated diseases. In Primary central nervous system lymphoma (PCNSL), expression of BCA-1 by malignant lymphocytes and vascular endothelium may influence tumor development and localization to central nervous system (CNS). In T-lymphocytes, CXCL13 expression is thought to reflect a germinal center origin of the T-cell. CXCL13 expression may also provide an additional useful tool for the diagnosis of Angioimmunoblastic T-cell lymphoma (AITL). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Canine BCA-1 / CXCL13 Protein (TMPY-03708) |
| Antigen Species | Canine |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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