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Anti-BACE1 Antibody (2J206) is an antibody targeting BACE1. Anti-BACE1 Antibody (2J206) can be used in ELISA, WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $209 | 7-10 days | |
100 μL | $349 | 7-10 days |
Description | Antibody Type: Recombinant Monoclonal Application: ELISA, WB Reactivity: Human, Mouse, Rat |
Alias | β-site APP-cleaving enzyme 1, HSPC104, beta-site APP-cleaving enzyme 1, BACE, ASP2 |
Ig Type | Rabbit IgG |
Clone | 2J206 |
Reactivity | Human, Mouse, Rat |
Verified Activity | Western Blot -Positive WB detected in: MCF-7 whole cell lysate, Rat brain tissue, Mouse brain tissue -All lanes: BACE1 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 56, 53, 52, 49, 46, 43 kDa -Observed band size: 72 kDa |
Application | ELISA, WB |
Recommended Dose | WB:1:500-1:5000. |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network. Endoplasmic reticulum. Endosome. Cell surface. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Membrane raft. Lysosome. Late endosome. Early endosome. Recycling endosome. Cell projection, axon. Cell projection, dendrite. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves CHL1. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human BACE1 |
Antigen Species | Human |
Gene ID | 23621 |
Uniprot ID | |
Biology Area | Neuroscience, Cell biology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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