Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bictegravir Sodium (GS-9883 Sodium) is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir Sodium exhibits potent and selective anti-HIV activity and low cytotoxicity
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 40.00 | |
5 mg | In stock | $ 61.00 | |
10 mg | In stock | $ 97.00 | |
25 mg | In stock | $ 198.00 | |
50 mg | In stock | $ 382.00 | |
100 mg | In stock | $ 569.00 | |
500 mg | In stock | $ 1,250.00 |
Description | Bictegravir Sodium (GS-9883 Sodium) is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir Sodium exhibits potent and selective anti-HIV activity and low cytotoxicity |
Targets&IC50 | HIV-1 integrase:7.5 nM |
In vitro | Bictegravir Sodium potently inhibits HIV-1 replication in both MT-2 and MT-4 cells with EC50s of 1.5 and 2.4 nM, respectively, and selectivity indices (50% cytotoxic concentration [CC50]/EC50) of ∼6,800 in MT-2 cells and ∼1,500 in MT-4 cells[1]. |
Synonyms | GS-9883 Sodium |
Molecular Weight | 471.36 |
Formula | C21H17F3N3NaO5 |
CAS No. | 1807988-02-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 15.3 mg/mL (32.5 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Bictegravir Sodium 1807988-02-8 Microbiology/Virology Proteases/Proteasome HIV Protease GS-9883 Sodium inhibitor inhibit