Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

(1α,1'S,4β)-Lanabecestat

😃Good
Catalog No. T10014Cas No. 1384082-96-5
Alias (1α,1'S,4β)-AZD3293

(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzyme 1 (BACE1) inhibitor with IC50 values of 2.2 nM in the TR-FRET assay and 0.28 nM in the sAPPp release assay.

(1α,1'S,4β)-Lanabecestat
Other Forms of (1α,1'S,4β)-Lanabecestat:

(1α,1'S,4β)-Lanabecestat

😃Good
Catalog No. T10014Alias (1α,1'S,4β)-AZD3293Cas No. 1384082-96-5
(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzyme 1 (BACE1) inhibitor with IC50 values of 2.2 nM in the TR-FRET assay and 0.28 nM in the sAPPp release assay.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$1085 days5 days
50 mg$7288-10 weeks8-10 weeks
100 mg$1,2408-10 weeks8-10 weeks
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Resource Download

Product Introduction

Bioactivity
Description
(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzyme 1 (BACE1) inhibitor with IC50 values of 2.2 nM in the TR-FRET assay and 0.28 nM in the sAPPp release assay.
Synonyms(1α,1'S,4β)-AZD3293
Chemical Properties
Molecular Weight412.53
FormulaC26H28N4O
Cas No.1384082-96-5
Relative Density.1.23 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 250 mg/mL (606.02 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4241 mL12.1203 mL24.2407 mL121.2033 mL
5 mM0.4848 mL2.4241 mL4.8481 mL24.2407 mL
10 mM0.2424 mL1.2120 mL2.4241 mL12.1203 mL
20 mM0.1212 mL0.6060 mL1.2120 mL6.0602 mL
50 mM0.0485 mL0.2424 mL0.4848 mL2.4241 mL
100 mM0.0242 mL0.1212 mL0.2424 mL1.2120 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

(1a,1'S,4b)-AZD 3293(1α,1'S,4β)-AZD 3293(1α,1'S,4β) Lanabecestat(1alpha,1'S,4beta)-Lanabecestat(1α,1'S,4β)-AZD-3293(1a,1'S,4b)-AZD-3293(1a,1'S,4b)-AZD3293(1alpha,1'S,4beta)-AZD-3293(1a,1'S,4b)-Lanabecestat(1alpha,1'S,4beta)-AZD3293(1alpha,1'S,4beta)-AZD 3293(1α,1'S,4β)Lanabecestat(1α,1'S,4β)-Lanabecestat
Related Tags: buy (1α,1'S,4β)-Lanabecestat | purchase (1α,1'S,4β)-Lanabecestat | (1α,1'S,4β)-Lanabecestat cost | order (1α,1'S,4β)-Lanabecestat | (1α,1'S,4β)-Lanabecestat chemical structure | (1α,1'S,4β)-Lanabecestat formula | (1α,1'S,4β)-Lanabecestat molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.