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Salicylic acid

Name: Salicylic acid
Brand: TargetMol
SKU: T0649
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0649Cas No. 69-72-7

Alias 2-Hydroxybenzoic acid

Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.

Salicylic acid

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Purity: 98.83%

Catalog No. T0649Alias 2-Hydroxybenzoic acidCas No. 69-72-7

Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.

Pack Size	Price	Availability
500 mg	$33	In Stock
10 g	$50	In Stock
50 g	$74	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Purity:98.83%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.
In vitro	Salicylic acid (SA) is a phenolic phytohormone involved in plant defence against pathogens. It significantly stimulated PON1 activity in a concentration dependent manner[3].
In vivo	Although oral SA (5.5 mg/kg body weight) during the Hg(0) exposure did not reduce the Hg levels in these organs, it effectively counteracted the Hg(0)-induced growth inhibition, and improved the behavioral performance, accompanied by a series of ameliorations in the antioxidative defense and anti-inflammatory response[2].
Synonyms	2-Hydroxybenzoic acid

Chemical Properties

Molecular Weight	138.12
Formula	C₇H₆O₃
Cas No.	69-72-7
Smiles	OC(=O)C1=CC=CC=C1O
Relative Density.	1.44. Temperature:20 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 141 mg/mL (1020.85 mM), Sonication is recommended.

H2O: 1 mg/mL (7.24 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	7.2401 mL	36.2004 mL	72.4008 mL	362.0041 mL
5 mM	1.4480 mL	7.2401 mL	14.4802 mL	72.4008 mL

DMSO

	1mg	5mg	10mg	50mg
10 mM	0.7240 mL	3.6200 mL	7.2401 mL	36.2004 mL
20 mM	0.3620 mL	1.8100 mL	3.6200 mL	18.1002 mL
50 mM	0.1448 mL	0.7240 mL	1.4480 mL	7.2401 mL
100 mM	0.0724 mL	0.3620 mL	0.7240 mL	3.6200 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc