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[Sar1, Ile8]-Angiotensin II TFA

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Catalog No. TP1224
Alias AngiotensinII TFA, Angiotensin 2 TFA

[Sar1, Ile8]-Angiotensin II (TFA) is a peptide compound that affects vascular smooth muscle by causing contraction of normal arteries and inducing hypertrophy or hyperplasia in cultured cells or diseased vessels.

[Sar1, Ile8]-Angiotensin II TFA

[Sar1, Ile8]-Angiotensin II TFA

😃Good
Catalog No. TP1224Alias AngiotensinII TFA, Angiotensin 2 TFA
[Sar1, Ile8]-Angiotensin II (TFA) is a peptide compound that affects vascular smooth muscle by causing contraction of normal arteries and inducing hypertrophy or hyperplasia in cultured cells or diseased vessels.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$90InquiryInquiry
50 mg$319InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
[Sar1, Ile8]-Angiotensin II (TFA) is a peptide compound that affects vascular smooth muscle by causing contraction of normal arteries and inducing hypertrophy or hyperplasia in cultured cells or diseased vessels.
SynonymsAngiotensinII TFA, Angiotensin 2 TFA
Chemical Properties
Molecular Weight1082.18
FormulaC48H74F3N13O12
Relative Density.no data available
Sequence{SAR}-Arg-Val-Tyr-Ile-His-Pro-Ile
Sequence Short{SAR}-RVYIHPI
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 50 mg/mL (46.2 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM0.9241 mL4.6203 mL9.2406 mL46.2030 mL
5 mM0.1848 mL0.9241 mL1.8481 mL9.2406 mL
10 mM0.0924 mL0.4620 mL0.9241 mL4.6203 mL
20 mM0.0462 mL0.2310 mL0.4620 mL2.3102 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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