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Anti-IL-22RA1 Antibody (6H79)
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Catalog No. TMAY-00736
Alias interleukin 22 receptor, α1, interleukin 22 receptor, alpha 1
Anti-IL-22RA1 Antibody (6H79) is a Mouse antibody targeting IL-22RA1. Anti-IL-22RA1 Antibody (6H79) can be used in ELISA.
Anti-IL-22RA1 Antibody (6H79)
Anti-IL-22RA1 Antibody (6H79)
😃Good
Catalog No. TMAY-00736Alias interleukin 22 receptor, α1, interleukin 22 receptor, alpha 1
Anti-IL-22RA1 Antibody (6H79) is a Mouse antibody targeting IL-22RA1. Anti-IL-22RA1 Antibody (6H79) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | interleukin 22 receptor, α1, interleukin 22 receptor, alpha 1 |
| Ig Type | Mouse IgG1 |
| Clone | 6H79 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL22RA1 (rh IL22RA1; TMPY-07014; NP_067081.2; Met1-Thr228). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal skin as well as in psoriatic skin lesions. Overexpression of IL-22R can be detected in synovial fluid cells from rheumatoid arthritis and spondyloarthropathy patients. IL-22R is a component of the receptor for IL20, IL22, and IL24. The component of IL-22R formed by IL22RA1 and IL10RB enables IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptors for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. IL-22R mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human IL22RA1 Protein (TMPY-07014) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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