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Anti-IL-22RA1 Antibody (6H79) (Synonyms: interleukin 22 receptor, α1, interleukin 22 receptor, alpha 1)

Name: Anti-IL-22RA1 Antibody (6H79)
Brand: TargetMol
SKU: TMAY-00736
Rating: 4.5 (1 reviews)

Catalog No. TMAY-00736 Copy Product Info

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Anti-IL-22RA1 Antibody (6H79) is a Mouse antibody targeting IL-22RA1. Anti-IL-22RA1 Antibody (6H79) can be used in ELISA.

Anti-IL-22RA1 Antibody (6H79)

Copy Product Info

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Catalog No. TMAY-00736

Synonyms interleukin 22 receptor, α1, interleukin 22 receptor, alpha 1

Anti-IL-22RA1 Antibody (6H79) is a Mouse antibody targeting IL-22RA1. Anti-IL-22RA1 Antibody (6H79) can be used in ELISA.

Anti-IL-22RA1 Antibody
(6H79)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$199	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-IL-22RA1 Antibody (6H79) is a Mouse antibody targeting IL-22RA1. Anti-IL-22RA1 Antibody (6H79) can be used in ELISA.
Synonyms	interleukin 22 receptor, α1, interleukin 22 receptor, alpha 1
Ig Type	Mouse IgG1
Clone	6H79
Reactivity	Human
Specificity	Human IL22RA1
Application	ELISA
Recommended Dose	ELISA: 1:1000-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL22RA1 (rh IL22RA1; TMPY-07014; NP_067081.2; Met1-Thr228). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal skin as well as in psoriatic skin lesions. Overexpression of IL-22R can be detected in synovial fluid cells from rheumatoid arthritis and spondyloarthropathy patients. IL-22R is a component of the receptor for IL20, IL22, and IL24. The component of IL-22R formed by IL22RA1 and IL10RB enables IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptors for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. IL-22R mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human IL22RA1 Protein (TMPY-07014)
Antigen Species	Human

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

interleukin 22 receptor, α 1interleukin 22 receptor, a 1

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