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Anti-IL-22RA1 Antibody (6H79)

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Catalog No. TMAY-00736
Alias interleukin 22 receptor, α1, interleukin 22 receptor, alpha 1

Anti-IL-22RA1 Antibody (6H79) is a Mouse antibody targeting IL-22RA1. Anti-IL-22RA1 Antibody (6H79) can be used in ELISA.

Anti-IL-22RA1 Antibody (6H79)

Anti-IL-22RA1 Antibody (6H79)

😃Good
Catalog No. TMAY-00736Alias interleukin 22 receptor, α1, interleukin 22 receptor, alpha 1
Anti-IL-22RA1 Antibody (6H79) is a Mouse antibody targeting IL-22RA1. Anti-IL-22RA1 Antibody (6H79) can be used in ELISA.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-IL-22RA1 Antibody (6H79) is a Mouse antibody targeting IL-22RA1. Anti-IL-22RA1 Antibody (6H79) can be used in ELISA.
Aliasinterleukin 22 receptor, α1, interleukin 22 receptor, alpha 1
Ig Type
Monoclonal Mouse IgG1
Clone
6H79
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL22RA1 (rh IL22RA1; TMPY-07014; NP_067081.2; Met1-Thr228). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundIL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal skin as well as in psoriatic skin lesions. Overexpression of IL-22R can be detected in synovial fluid cells from rheumatoid arthritis and spondyloarthropathy patients. IL-22R is a component of the receptor for IL20, IL22, and IL24. The component of IL-22R formed by IL22RA1 and IL10RB enables IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptors for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. IL-22R mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human IL22RA1 Protein (TMPY-07014)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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