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Anti-TSC22D1 Antibody (9I490) is a Rabbit antibody targeting TSC22D1. Anti-TSC22D1 Antibody (9I490) can be used in ICC/IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $270 | 7-10 days |
Description | Anti-TSC22D1 Antibody (9I490) is a Rabbit antibody targeting TSC22D1. Anti-TSC22D1 Antibody (9I490) can be used in ICC/IF. |
Alias | TSC22 domain family, member 1, TSC22, TGFB1I4, Ptg-2 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 9I490 |
Reactivity | Human |
Verified Activity | Immunofluorescence staining of Human TSC22D1 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human TSC22D1 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to nucleus and cytoplasm. |
Application | ICC/IF |
Recommended Dose | ICC-IF: 1:20-1:100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human TSC22D1 (rh TSC22D1; TMPY-02400; Q15714-2; Met1-Ala144). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | TSC22 domain family, member 1 (TSC22D1) is one of the TGF-beta-stimulated clone-22 (TSC-22). TSC-22 was reported to be a differentiation-inducing factor that negatively regulates the growth of salivary gland cancer cells. TSC22D1, which encodes transforming growth factor beta-stimulated clone 22 (TSC-22), is thought to be a tumor suppressor because its expression is lost in many glioblastoma, salivary gland, and prostate cancers. TSC-22 is the founding member of the TSC-22/DIP/Bun family of leucine zipper transcription factors. TSC-22 may play an important role in maintaining the differentiated phenotype in salivary gland tumors, and may be a possible target of leukemia therapy. TSC22D1 forms homodimers via its conserved leucine zipper domain and heterodimerizes with TSC22D4. TSC22D1 has transcriptional repressor activity. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human TSC22D1 protein (TMPY-02400) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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