Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Compound 6, fac-[Re(CO)3(L6)(H2O)][NO3], a rhenium(I) tricarbonyl aqua complex, serves as an anticancer agent by disrupting mitochondrial function. It exhibits cytotoxicity against prostate cancer cells with an IC50 of 50 nM in PC-3 cells. This compound predominantly localizes in the nucleus, impairs ATP production, and induces apoptosis in PC3 cells without causing necrosis, pyroptosis, or autophagy [1].
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Description | Compound 6, fac-[Re(CO)3(L6)(H2O)][NO3], a rhenium(I) tricarbonyl aqua complex, serves as an anticancer agent by disrupting mitochondrial function. It exhibits cytotoxicity against prostate cancer cells with an IC50 of 50 nM in PC-3 cells. This compound predominantly localizes in the nucleus, impairs ATP production, and induces apoptosis in PC3 cells without causing necrosis, pyroptosis, or autophagy [1]. |
Molecular Weight | 702.67 |
Formula | C24H14N5O7ReS |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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fac-[Re(CO)3(L6)(H2O)][NO3] Apoptosis inhibitor inhibit