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Anti-M-CSF/CSF1 Antibody (4C549)
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Catalog No. TMAY-02062
Alias M-CSF, MCSF, CSF-1, colony stimulating factor 1 (macrophage)
Anti-M-CSF/CSF1 Antibody (4C549) is a Rabbit antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Antibody (4C549) can be used in ELISA(Det).
Anti-M-CSF/CSF1 Antibody (4C549)
Anti-M-CSF/CSF1 Antibody (4C549)
😃Good
Catalog No. TMAY-02062Alias M-CSF, MCSF, CSF-1, colony stimulating factor 1 (macrophage)
Anti-M-CSF/CSF1 Antibody (4C549) is a Rabbit antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Antibody (4C549) can be used in ELISA(Det).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $94 | 7-10 days | |
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-M-CSF/CSF1 Antibody (4C549) is a Rabbit antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Antibody (4C549) can be used in ELISA(Det). |
| Alias | M-CSF, MCSF, CSF-1, colony stimulating factor 1 (macrophage) |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4C549 |
| Reactivity | Human |
| Application | ELISA(Det) |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human M-CSF/CSF-1 (rh M-CSF/CSF-1; TMPY-00127; NP_757349.1; Met1-Asn190). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression. |
| Conjucates | Unconjugated |
| Others Formats | HRP |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human M-CSF/CSF-1 Protein (TMPY-00127) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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