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γ-Cyclodextrin

Name: γ-Cyclodextrin
Brand: TargetMol
SKU: T20682
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20682Cas No. 17465-86-0

Alias Ringdex C, gamma-Dextrin, Gamma cyclodextrin, Cyclooctaamylose

γ-Cyclodextrin (Ringdex C) is a cycloamylose composed of eight alpha-(1->4) linked D-glucopyranose units found in some foods.

γ-Cyclodextrin

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Purity: 98.56%

Catalog No. T20682Alias Ringdex C, gamma-Dextrin, Gamma cyclodextrin, CyclooctaamyloseCas No. 17465-86-0

γ-Cyclodextrin (Ringdex C) is a cycloamylose composed of eight alpha-(1->4) linked D-glucopyranose units found in some foods.

Pack Size	Price	USA Warehouse	Global Warehouse
500 mg	$42	In Stock	In Stock
1 g	$58	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.56%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

γ-Cyclodextrin AI Summary

γ-Cyclodextrin demonstrates solubility in water with a value of 23.2 grams per 100 milliliters. It exhibits antiviral activity against SARS-CoV-2 by inhibiting cytotoxicity of VERO-6 cells. The compound was tested at a concentration of 10 µM for 48 hours exposure to 0.01 MOI SARS-CoV-2 virus using high content imaging. The IC50 value for this activity is greater than 20,000.0 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	γ-Cyclodextrin (Ringdex C) is a cycloamylose composed of eight alpha-(1->4) linked D-glucopyranose units found in some foods.
Synonyms	Ringdex C, gamma-Dextrin, Gamma cyclodextrin, Cyclooctaamylose

Chemical Properties

Molecular Weight	1297.12
Formula	C₄₈H₈₀O₄₀
Cas No.	17465-86-0
Smiles	OC[C@H]1O[C@@H]2O[C@@H]3[C@@H](CO)O[C@H](O[C@@H]4[C@@H](CO)O[C@H](O[C@@H]5[C@@H](CO)O[C@H](O[C@@H]6[C@@H](CO)O[C@H](O[C@@H]7[C@@H](CO)O[C@H](O[C@@H]8[C@@H](CO)O[C@H](O[C@@H]9[C@@H](CO)O[C@H](O[C@H]1[C@H](O)[C@H]2O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O
Relative Density.	1.477 g/cm3. Temperature:20 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (50.11 mM), Sonication is recommended.

1 M NH4OH: 40 mg/mL (30.84 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (1.54 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

1 M NH4OH/DMSO

	1mg	5mg	10mg	50mg
1 mM	0.7709 mL	3.8547 mL	7.7094 mL	38.5469 mL
5 mM	0.1542 mL	0.7709 mL	1.5419 mL	7.7094 mL
10 mM	0.0771 mL	0.3855 mL	0.7709 mL	3.8547 mL
20 mM	0.0385 mL	0.1927 mL	0.3855 mL	1.9273 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0154 mL	0.0771 mL	0.1542 mL	0.7709 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc