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Anti-Mouse IL-2 Antibody (S4B6-1)

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Catalog No. T9901A-172 Copy Product Info
Purity: 95%
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Anti-Mouse IL-2 Antibody (S4B6-1) is a monoclonal inhibitory antibody targeting mouse interleukin-2. It can reduce the level of CD4+ T cells, upregulate the proportion of regulatory T cells (Tregs), and induce Th17 cell differentiation. It is suitable for mechanism studies related to tumors such as melanoma.

Anti-Mouse IL-2 Antibody
(S4B6-1)

Pack SizePriceUSA StockGlobal StockQuantity
1 mg$56-In Stock
5 mg$232-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-Mouse IL-2 Antibody (S4B6-1) is a monoclonal inhibitory antibody targeting mouse interleukin-2. It can reduce the level of CD4+ T cells, upregulate the proportion of regulatory T cells (Tregs), and induce Th17 cell differentiation. It is suitable for mechanism studies related to tumors such as melanoma.
In vitro
Anti-Mouse IL-2 Antibody (S4B6-1) induces Th17 cell differentiation at 10 μg/mL for 72 hours [2].
In vivo
Anti-Mouse IL-2 Antibody (S4B6-1) (100 µg, intraperitoneal injection, every 3 days) in combination with IL-2 monoclonal antibody (JES6-1A12) promotes tumor growth and reduces survival rate in female C57BL/6J mice bearing B16F10 tumors [1].
Anti-Mouse IL-2 Antibody (S4B6-1) (150 μg, intraperitoneal injection, every 3 days for 2 weeks) reduces the number of central regulatory T cells (cTregs) in C57BL/6 mice bearing B16.Flt3L tumors [3].
Clone
S4B6-1
Reactivity
Mouse
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-2
Chemical Properties
Molecular Weight150 kDa
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-Mouse IL-2 Antibody (S4B6-1) in vivo | Anti-Mouse IL-2 Antibody (S4B6-1) in vitro | Anti-Mouse IL-2 Antibody (S4B6-1) molecular weight