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Anti-Mouse IL-2 Antibody (S4B6-1) is a monoclonal inhibitory antibody targeting mouse interleukin-2. It can reduce the level of CD4+ T cells, upregulate the proportion of regulatory T cells (Tregs), and induce Th17 cell differentiation. It is suitable for mechanism studies related to tumors such as melanoma.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $56 | Inquiry | Inquiry | |
| 5 mg | $232 | Inquiry | Inquiry |
| Description | Anti-Mouse IL-2 Antibody (S4B6-1) is a monoclonal inhibitory antibody targeting mouse interleukin-2. It can reduce the level of CD4+ T cells, upregulate the proportion of regulatory T cells (Tregs), and induce Th17 cell differentiation. It is suitable for mechanism studies related to tumors such as melanoma. |
| In vitro | Anti-Mouse IL-2 Antibody (S4B6-1) induces Th17 cell differentiation at 10 μg/mL for 72 hours [2]. |
| In vivo | Anti-Mouse IL-2 Antibody (S4B6-1) (100 µg, intraperitoneal injection, every 3 days) in combination with IL-2 monoclonal antibody (JES6-1A12) promotes tumor growth and reduces survival rate in female C57BL/6J mice bearing B16F10 tumors [1]. Anti-Mouse IL-2 Antibody (S4B6-1) (150 μg, intraperitoneal injection, every 3 days for 2 weeks) reduces the number of central regulatory T cells (cTregs) in C57BL/6 mice bearing B16.Flt3L tumors [3]. |
| Clone | S4B6-1 |
| Reactivity | Mouse |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-2 |
| Molecular Weight | 150 kDa |
| Storage | Store at -20°C Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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