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Helicid (Synonyms: Hilicidum, Helicide, 4-formylphenyl-O-β-d-allopyranoside)

Name: Helicid
Brand: TargetMol
SKU: T3428
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T3428 Copy Product Info

Purity: 99.68%

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Helicid (Helicide) is a medicine available in a number of countries worldwide.

Helicid

Copy Product Info

🥰Excellent

Catalog No. T3428

Synonyms Hilicidum, Helicide, 4-formylphenyl-O-β-d-allopyranoside

Helicid (Helicide) is a medicine available in a number of countries worldwide.

Cas No. 80154-34-3

Pack Size	Price	USA Stock	Global Stock	Quantity
1 g	$34	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.68%

Color:White

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COA LCMS HNMR

Product Introduction

Helicid AI Summary

Helicid exhibits a variety of bioactivities. It shows inhibitory activity against SSADH and GABAT with an IC50 greater than 1,000,000 nM. Additionally, it inhibits mushroom tyrosinase with an IC50 value of 2,540,000 nM in the oxidation of 3,4-dihydroxy-L-phenylalanine. At a concentration of 0.1 mM, it demonstrates a 10% inhibition of mushroom tyrosinase. Helicid also shows an inhibition of 24.84% on Torpedo californica acetylcholinesterase (AChE) at a 1 mM concentration, as measured by Ellman's method, indicating potential AChE inhibitory activity. Moreover, it exhibits antiproliferative activity against human MCF7 cells with a relatively weak effect, having an IC50 greater than 20,000 nM as determined by the Sulforhodamine B (SRB) assay..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Helicid (Helicide) is a medicine available in a number of countries worldwide.
Synonyms	Hilicidum, Helicide, 4-formylphenyl-O-β-d-allopyranoside

Chemical Properties

Molecular Weight	284.26
Formula	C₁₃H₁₆O₇
Cas No.	80154-34-3
Smiles	O([C@@H]1O[C@H](CO)[C@@H](O)[C@@H](O)[C@H]1O)C2=CC=C(C=O)C=C2
Relative Density.	1.510 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (193.48 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.04 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5179 mL	17.5895 mL	35.1791 mL	175.8953 mL
5 mM	0.7036 mL	3.5179 mL	7.0358 mL	35.1791 mL
10 mM	0.3518 mL	1.7590 mL	3.5179 mL	17.5895 mL
20 mM	0.1759 mL	0.8795 mL	1.7590 mL	8.7948 mL
50 mM	0.0704 mL	0.3518 mL	0.7036 mL	3.5179 mL
100 mM	0.0352 mL	0.1759 mL	0.3518 mL	1.7590 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc