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RNase L-IN-1

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Catalog No. T79488

RNase L-IN-1 (compound 17a) functions as an inhibitor of RNase L (Ribonuclease L), an enzyme responsible for RNA degradation to inhibit viral replication and mediate innate immune responses and inflammation [1].

RNase L-IN-1

RNase L-IN-1

😃Good
Purity: 98.55%
Catalog No. T79488
RNase L-IN-1 (compound 17a) functions as an inhibitor of RNase L (Ribonuclease L), an enzyme responsible for RNA degradation to inhibit viral replication and mediate innate immune responses and inflammation [1].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$212-In Stock
5 mg$5827-10 days7-10 days
10 mg$8327-10 days7-10 days
25 mg$1,3357-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.55%
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COA HNMR

Product Introduction

Bioactivity
Description
RNase L-IN-1 (compound 17a) functions as an inhibitor of RNase L (Ribonuclease L), an enzyme responsible for RNA degradation to inhibit viral replication and mediate innate immune responses and inflammation [1].
Chemical Properties
Molecular Weight542.67
FormulaC27H35FN6O3S
SmilesFC1=CC=CC(NC2=C(C(NCCN)=O)C(/C(S2)=C\C3=C(C)C(C(NCCN(CC)CC)=O)=C(C)N3)=O)=C1
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 6 mg/mL (11.06 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8427 mL9.2137 mL18.4274 mL92.1370 mL
5 mM0.3685 mL1.8427 mL3.6855 mL18.4274 mL
10 mM0.1843 mL0.9214 mL1.8427 mL9.2137 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

RNase L
Related Tags: buy RNase L-IN-1 | purchase RNase L-IN-1 | RNase L-IN-1 cost | order RNase L-IN-1 | RNase L-IN-1 chemical structure | RNase L-IN-1 formula | RNase L-IN-1 molecular weight
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