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IMB-XH1

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Catalog No. T16028Cas No. 292057-76-2
Alias Mcl1-IN-2

IMB-XH1 (Mcl1-IN-2) is a myeloid cell factor 1 (Mcl-1) inhibitor.

IMB-XH1

IMB-XH1

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Purity: 98%
Catalog No. T16028Alias Mcl1-IN-2Cas No. 292057-76-2
IMB-XH1 (Mcl1-IN-2) is a myeloid cell factor 1 (Mcl-1) inhibitor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$50In StockIn Stock
5 mg$119In StockIn Stock
10 mg$197In StockIn Stock
25 mg$332In StockIn Stock
50 mg$478In StockIn Stock
100 mg$653In StockIn Stock
200 mg$879-In Stock
1 mL x 10 mM (in DMSO)$119In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
IMB-XH1 (Mcl1-IN-2) is a myeloid cell factor 1 (Mcl-1) inhibitor.
In vitro
Mcl1-IN-2 is an inhibitor of Mcl-1 , though without a reported IC50 value.
SynonymsMcl1-IN-2
Chemical Properties
Molecular Weight333.41
FormulaC19H15N3OS
Cas No.292057-76-2
SmilesOc1c(ccc2cccnc12)C(Nc1ccccn1)c1cccs1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 33.33 mg/mL (99.97 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9993 mL14.9966 mL29.9931 mL149.9655 mL
5 mM0.5999 mL2.9993 mL5.9986 mL29.9931 mL
10 mM0.2999 mL1.4997 mL2.9993 mL14.9966 mL
20 mM0.1500 mL0.7498 mL1.4997 mL7.4983 mL
50 mM0.0600 mL0.2999 mL0.5999 mL2.9993 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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