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Anti-CEACAM3 Antibody (6H164)
😃Good
Catalog No. TMAY-02151
Alias W282, W264, MGC119875, CGM1, CEA, CD66D, carcinoembryonic antigen related cell adhesion molecule 3
Anti-CEACAM3 Antibody (6H164) is a Mouse antibody targeting CEACAM3. Anti-CEACAM3 Antibody (6H164) can be used in ELISA.
Anti-CEACAM3 Antibody (6H164)
Anti-CEACAM3 Antibody (6H164)
😃Good
Catalog No. TMAY-02151Alias W282, W264, MGC119875, CGM1, CEA, CD66D, carcinoembryonic antigen related cell adhesion molecule 3
Anti-CEACAM3 Antibody (6H164) is a Mouse antibody targeting CEACAM3. Anti-CEACAM3 Antibody (6H164) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CEACAM3 Antibody (6H164) is a Mouse antibody targeting CEACAM3. Anti-CEACAM3 Antibody (6H164) can be used in ELISA. |
| Alias | W282, W264, MGC119875, CGM1, CEA, CD66D, carcinoembryonic antigen related cell adhesion molecule 3 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 6H164 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CEACAM3 / CD66d (rh CEACAM3 / CD66d; TMPY-01850; NP_001806.2; Met 1-Gly 155). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. Monoclonal antibodies grouped in the CD66 cluster recognize CEACAM members. Ectopic CD66 expression is commonly detected in B-cell lineage acute lymphoblastic leukemia (ALL). CEACAM3 mediates phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3. CEACAM3 is characterized by rapid stimulation of the GTPase Rac. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CEACAM3 / CD66d protein (TMPY-01850) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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