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Roburic acid

Name: Roburic acid
Brand: TargetMol
SKU: T3883
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T3883Cas No. 6812-81-3

Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.

Roburic acid

🥰Excellent

Purity: 99.88%

Catalog No. T3883Cas No. 6812-81-3

Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.

Pack Size	Price	Availability
1 mg	$45	In Stock
5 mg	$97	In Stock
10 mg	$189	In Stock
25 mg	$328	In Stock
50 mg	$492	In Stock
1 mL x 10 mM (in DMSO)	$117	In Stock

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Batch Information

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Purity:99.88%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.
Targets&IC50	COX-2:9 μM (IC50), COX-1:5 μM (IC50)

Chemical Properties

Molecular Weight	440.7
Formula	C₃₀H₄₈O₂
Cas No.	6812-81-3
Smiles	C[C@@H]1CC[C@]2(C)CC[C@]3(C)C(=CC[C@@H]4[C@@](C)(CCC(O)=O)[C@@H](CC[C@@]34C)C(C)=C)[C@@H]2[C@H]1C
Relative Density.	1.02 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from moisture,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (136.15 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2691 mL	11.3456 mL	22.6912 mL	113.4559 mL
5 mM	0.4538 mL	2.2691 mL	4.5382 mL	22.6912 mL
10 mM	0.2269 mL	1.1346 mL	2.2691 mL	11.3456 mL
20 mM	0.1135 mL	0.5673 mL	1.1346 mL	5.6728 mL
50 mM	0.0454 mL	0.2269 mL	0.4538 mL	2.2691 mL
100 mM	0.0227 mL	0.1135 mL	0.2269 mL	1.1346 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc