Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Beclin1-ATG14L Interaction Inhibitor 1 (COM 19) is a selective inhibitor targeting the specific interaction between Beclin1 and ATG14L. It impedes the formation of complex I in the lipid kinase VPS34, thus inhibiting autophagy, while leaving complex II intact, which relies on the Beclin 1-UVRAG interaction for its integrity and is essential for vesicle transport [1].
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Description | Beclin1-ATG14L Interaction Inhibitor 1 (COM 19) is a selective inhibitor targeting the specific interaction between Beclin1 and ATG14L. It impedes the formation of complex I in the lipid kinase VPS34, thus inhibiting autophagy, while leaving complex II intact, which relies on the Beclin 1-UVRAG interaction for its integrity and is essential for vesicle transport [1]. |
Molecular Weight | 468.53 |
Formula | C23H24N4O5S |
CAS No. | 1243063-73-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Beclin1-ATG14L interaction inhibitor 1 1243063-73-1 Autophagy inhibitor inhibit