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NCRW0005-F05

Name: NCRW0005-F05
Brand: TargetMol
SKU: T60199
Price: 89 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60199Cas No. 342779-66-2

NCRW0005-F05 is a potent agonist of orphan G-protein coupled receptor GPR139 with an IC 50 value of 0.21 μM. NCRW0005-F05 can be used to research diabetes, obesity and Parkinson's disease [1].

NCRW0005-F05

🥰Excellent

Purity: 99.97%

Catalog No. T60199Cas No. 342779-66-2

NCRW0005-F05 is a potent agonist of orphan G-protein coupled receptor GPR139 with an IC 50 value of 0.21 μM. NCRW0005-F05 can be used to research diabetes, obesity and Parkinson's disease [1].

Pack Size	Price	Availability
10 mg	$43	In Stock
25 mg	$89	In Stock
50 mg	Preferential	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock

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Batch Information

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Purity:99.97%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

NCRW0005-F05 is a potent agonist of orphan G-protein coupled receptor GPR139 with an IC 50 value of 0.21 μM. NCRW0005-F05 can be used to research diabetes, obesity and Parkinson's disease [1].

Chemical Properties

Molecular Weight	289.28
Formula	C₁₆H₁₃F₂NO₂
Cas No.	342779-66-2
Smiles	COc1ccc(cc1)C1N(C(=O)C1(F)F)c1ccccc1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (311.12 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4569 mL	17.2843 mL	34.5686 mL	172.8429 mL
5 mM	0.6914 mL	3.4569 mL	6.9137 mL	34.5686 mL
10 mM	0.3457 mL	1.7284 mL	3.4569 mL	17.2843 mL
20 mM	0.1728 mL	0.8642 mL	1.7284 mL	8.6421 mL
50 mM	0.0691 mL	0.3457 mL	0.6914 mL	3.4569 mL
100 mM	0.0346 mL	0.1728 mL	0.3457 mL	1.7284 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc