Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TUS-007, a modified CANDDY (Chemical knockdown with Affinity aNd Degradation DYnamics) molecule originally derived from a proteasome inhibitor, scarcely affects proteasome activity. It is a potent, orally active degrader of KRAS G12D/V, effective in cell-free chemical knockdown of KRAS G12D/V. Furthermore, TUS-007 has been shown to suppress tumor growth [1].
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50 mg | Inquiry | Inquiry |
Description | TUS-007, a modified CANDDY (Chemical knockdown with Affinity aNd Degradation DYnamics) molecule originally derived from a proteasome inhibitor, scarcely affects proteasome activity. It is a potent, orally active degrader of KRAS G12D/V, effective in cell-free chemical knockdown of KRAS G12D/V. Furthermore, TUS-007 has been shown to suppress tumor growth [1]. |
Molecular Weight | 845.86 |
Formula | C44H54Cl2N8O5 |
CAS No. | 2227029-18-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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TUS-007 2227029-18-5 inhibitor inhibit