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Anti-TAG1/Contactin 2 Antibody (9O918)
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Catalog No. TMAY-00852
Alias Tax, TAG-1, D130012K04Rik, contactin 2 (axonal)
Anti-TAG1/Contactin 2 Antibody (9O918) is a Mouse antibody targeting TAG1/Contactin 2. Anti-TAG1/Contactin 2 Antibody (9O918) can be used in ELISA.
Anti-TAG1/Contactin 2 Antibody (9O918)
Anti-TAG1/Contactin 2 Antibody (9O918)
😃Good
Catalog No. TMAY-00852Alias Tax, TAG-1, D130012K04Rik, contactin 2 (axonal)
Anti-TAG1/Contactin 2 Antibody (9O918) is a Mouse antibody targeting TAG1/Contactin 2. Anti-TAG1/Contactin 2 Antibody (9O918) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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| Description | Anti-TAG1/Contactin 2 Antibody (9O918) is a Mouse antibody targeting TAG1/Contactin 2. Anti-TAG1/Contactin 2 Antibody (9O918) can be used in ELISA. |
| Alias | Tax, TAG-1, D130012K04Rik, contactin 2 (axonal) |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 9O918 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CNTN2 (rhCNTN2; TMPY-00721; Met1-Asn1012; NP_005067.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2 (TAG-1), Contactin-3 (BIG-1), BIG-2, Contactin-5 (NB-2) and NB-3. Since their identification in the late 1980s, Contactin-1 and Contactin-2 have been studied extensively. Axonal expression and the neurite extension activity of Contactin-1 and Contactin-2 attracted researchers to study the function of these molecules in axon guidance during development. Contactin-1 and Contactin-2 have come to be known as the principal molecules in the function and maintenance of myelinated neurons. In contrast, the function of the other four members of this subgroup remained unknown until recently. Contactin-2, also known as CNTN2, is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. The human, rat, and chicken Contactin-2 are alternatively known as TAX1 (transiently-expressed axonal glycoprotein), TAG1 (transient axonal glycoprotein), and axonin-1, respectively. Human Contactin-2 shares approximately 91% and 75% amino acid sequence identity with rat and chicken Contactin-2, respectively. Contactin-2 is expressed by a subset of neuronal populations in the developing central nervous system (CNS) and peripheral nervous system (PNS). Contactin-2 is also expressed by oligodendrocytes and Schwann cells, which are myelinating glial cells of the CNS and PNS, respectively. Contactin-2 may play a role in the formation of axon connections in the developing nervous system. Contactin-2 is also involved in glial tumorigenesis and may provide a potential target for therapeutic intervention. During embryonic development, Contactin-2 interacts either in a homophilic, or heterophilic fashion with various transmembrane proteins. |
| Conjucates | Unconjugated |
| Immunogen | Human cell-derived rhCNTN2 (TMPY-00721) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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