Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SIAIS117, a potent Brigatinib-PROTAC degrader, effectively degrades the ALK G1202R point mutation through its design based on Brigatinib and VHL-1 conjunction. It inhibits the proliferation of SR and H2228 cancer cell lines, demonstrating potential anti-proliferative effects against small cell lung cancer [1].
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Description | SIAIS117, a potent Brigatinib-PROTAC degrader, effectively degrades the ALK G1202R point mutation through its design based on Brigatinib and VHL-1 conjunction. It inhibits the proliferation of SR and H2228 cancer cell lines, demonstrating potential anti-proliferative effects against small cell lung cancer [1]. |
Molecular Weight | 1111.77 |
Formula | C57H76ClN10O7PS |
CAS No. | 2353494-84-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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SIAIS117 2353494-84-3 inhibitor inhibit