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Anti-LOX-1 Antibody (4V907)
😃Good
Catalog No. TMAY-00993
Alias oxidized low density lipoprotein (lectin-like) receptor 1, OLR1, Oldlr1, Lox1
Anti-LOX-1 Antibody (4V907) is a Mouse antibody targeting LOX-1. Anti-LOX-1 Antibody (4V907) can be used in ELISA.
Anti-LOX-1 Antibody (4V907)
Anti-LOX-1 Antibody (4V907)
😃Good
Catalog No. TMAY-00993Alias oxidized low density lipoprotein (lectin-like) receptor 1, OLR1, Oldlr1, Lox1
Anti-LOX-1 Antibody (4V907) is a Mouse antibody targeting LOX-1. Anti-LOX-1 Antibody (4V907) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | oxidized low density lipoprotein (lectin-like) receptor 1, OLR1, Oldlr1, Lox1 |
| Ig Type | Mouse IgG2a |
| Clone | 4V907 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human OLR1/LOX1 (rh OLR1/LOX1; TMPY-02490; P78380; Ser61-Gln273). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-ligand receptor originally identified as the endothelial oxidized LDL receptor. OLR1 / LOX1 was isolated from an aortic endothelial cell, and recently it has been discovered in macrophages and vascular smooth muscle cells in artery vessels. The expression of LOX1 is induced by inflammatory stimuli and oxidative stimuli. This protein binds, internalizes, and degrades oxidized low-density lipoprotein. LOX1 may play an important role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP-2. In clinical, LOX1 is thought to be involved in the development of atherosclerotic lesions. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human OLR1/LOX1 Protein (TMPY-02490) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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