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Catalog No. T13177Cas No. 71395-14-7
Tocainide hydrochloride, a sodium channel blocker, inhibits the sodium channels in the pain-producing foci in nerve membranes. It is an orally effective antiarrhythmic agent, structurally and pharmacologically similar to lidocaine [1][2].
Taquidil
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Catalog No. T13177Cas No. 71395-14-7
Tocainide hydrochloride, a sodium channel blocker, inhibits the sodium channels in the pain-producing foci in nerve membranes. It is an orally effective antiarrhythmic agent, structurally and pharmacologically similar to lidocaine [1][2].
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $52 | 5 days | 5 days | |
| 1 mL x 10 mM (in DMSO) | $98 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | Tocainide hydrochloride, a sodium channel blocker, inhibits the sodium channels in the pain-producing foci in nerve membranes. It is an orally effective antiarrhythmic agent, structurally and pharmacologically similar to lidocaine [1][2]. |
| Targets&IC50 | Na+ channel: |
| In vivo | Tocainide (100 mg/kg) effectively reduces ventricular ectopic activity in unanesthetized dogs with coronary occlusion. Cessation of tocainide in models of digitalis toxicity and coronary occlusion rapidly causes a resurgence of ventricular ectopic activity [1]. |
| Molecular Weight | 228.718 |
| Formula | C11H17ClN2O |
| Cas No. | 71395-14-7 |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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