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5,6-dimethyl-2-Thiouracil

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Catalog No. T37344Cas No. 28456-54-4

5,6-dimethyl-2-Thiouracil is a heterocyclic building block that has been used in the synthesis of anti-HIV-1 pyrimidinones.1 It has also been used as an internal standard for the quantification of thyreostats, including 2-thiouracil, in bovine plasma.2

5,6-dimethyl-2-Thiouracil

5,6-dimethyl-2-Thiouracil

😃Good
Catalog No. T37344Cas No. 28456-54-4
5,6-dimethyl-2-Thiouracil is a heterocyclic building block that has been used in the synthesis of anti-HIV-1 pyrimidinones.1 It has also been used as an internal standard for the quantification of thyreostats, including 2-thiouracil, in bovine plasma.2
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 mg$17835 days35 days
1 g$31635 days35 days
5 g$1,29035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
5,6-dimethyl-2-Thiouracil is a heterocyclic building block that has been used in the synthesis of anti-HIV-1 pyrimidinones.1 It has also been used as an internal standard for the quantification of thyreostats, including 2-thiouracil, in bovine plasma.2
Chemical Properties
Molecular Weight156.21
FormulaC6H8N2OS
Cas No.28456-54-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF:PBS (pH 7.2) (1:4): 0.2 mg/mL (1.28 mM), Sonication is recommended.
DMSO: 10 mg/mL (64.02 mM), Sonication is recommended.
DMF: 15 mg/mL (96.02 mM), Sonication is recommended.
Solution Preparation Table
DMSO/DMF
1mg5mg10mg50mg
5 mM1.2803 mL6.4016 mL12.8033 mL64.0164 mL
10 mM0.6402 mL3.2008 mL6.4016 mL32.0082 mL
20 mM0.3201 mL1.6004 mL3.2008 mL16.0041 mL
50 mM0.1280 mL0.6402 mL1.2803 mL6.4016 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

5,6 dimethyl 2 Thiouracil5,6-dimethyl-2-Thiouracil5,6dimethyl2Thiouracil
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