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Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440)

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Catalog No. TMAC-01456

Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440) is a Rabbit antibody targeting Ferritin heavy chain 1/FTH1. Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440) can be used in WB,IHC,ICC.

Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440)

Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440)

😃Good
Catalog No. TMAC-01456
Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440) is a Rabbit antibody targeting Ferritin heavy chain 1/FTH1. Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440) can be used in WB,IHC,ICC.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440) is a Rabbit antibody targeting Ferritin heavy chain 1/FTH1. Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440) can be used in WB,IHC,ICC.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMammalian ferritins consist of 24 subunits made up of two types of poly-peptide chains, ferritin heavy chain and ferritin light chain, which each have unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of FeII, whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of FeIII. The most prominent role of mamma-lian ferritins is to provide iron-buffering capacity to cells. In addition to iron buffering, heavy chain ferritin is also involved in the regulation of thymidine biosynthesis via increased expression of cytoplasmic serine hydroxymethyltransferase, which is a limiting factor in thymidylate synthesis in MCF-7 cells. Light chain ferritin is involved in cataracts by at least two mechanisms: hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed; and oxidative stress, an important factor in the development of aging-related cataracts.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 21 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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