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Vudalimab

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Catalog No. T76728 Copy Product Info
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Vudalimab, a fully humanized bispecific monoclonal antibody, effectively inhibits both PD-1 and CTLA-4 immune checkpoint receptors. This dual action facilitates the selective activation of T-cells targeting tumors.
Vudalimab
Cas No. 2329669-72-7
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$247-In Stock
5 mg$645-In Stock
10 mg$987-In Stock
25 mgPreferential-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:>95% (SDS-PAGE); 98.93% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Vudalimab, a fully humanized bispecific monoclonal antibody, effectively inhibits both PD-1 and CTLA-4 immune checkpoint receptors. This dual action facilitates the selective activation of T-cells targeting tumors.
In vitro
Vudalimab has binding avidity and can promote T cell activation, including IL-2, CD45+ cells, and IFNγ[1].
In vivo
Vudalimab (administered every 2 days for 16 consecutive days. NSG mice were first engrafted with KG1a-luc cells, followed by engraftment with human peripheral blood mononuclear cells) enhances allogeneic anti-tumor responses in mice [1].
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetPD-1 & CTLA-4
Chemical Properties
Cas No.2329669-72-7
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Related Tags: Vudalimab in vivo | Vudalimab in vitro