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Vudalimab
Catalog No. T76728 Copy Product Info
🥰Excellent
Vudalimab, a fully humanized bispecific monoclonal antibody, effectively inhibits both PD-1 and CTLA-4 immune checkpoint receptors. This dual action facilitates the selective activation of T-cells targeting tumors.
Vudalimab
Copy Product Info🥰Excellent
Catalog No. T76728
Vudalimab, a fully humanized bispecific monoclonal antibody, effectively inhibits both PD-1 and CTLA-4 immune checkpoint receptors. This dual action facilitates the selective activation of T-cells targeting tumors.
Vudalimab
Cas No. 2329669-72-7
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | - | In Stock | |
| 5 mg | $645 | - | In Stock | |
| 10 mg | $987 | - | In Stock | |
| 25 mg | Preferential | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:>95% (SDS-PAGE); 98.93% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
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| Description | Vudalimab, a fully humanized bispecific monoclonal antibody, effectively inhibits both PD-1 and CTLA-4 immune checkpoint receptors. This dual action facilitates the selective activation of T-cells targeting tumors. |
| In vitro | Vudalimab has binding avidity and can promote T cell activation, including IL-2, CD45+ cells, and IFNγ[1]. |
| In vivo | Vudalimab (administered every 2 days for 16 consecutive days. NSG mice were first engrafted with KG1a-luc cells, followed by engraftment with human peripheral blood mononuclear cells) enhances allogeneic anti-tumor responses in mice [1]. |
| Reactivity | Human |
| Verified Activity | Immobilized Human PD-1 Protein (hFc) at 8 μg/mL can bind Vudalimab. The EC50 is 0.08912 μg/mL.
Immobilized Human CTLA4 Protein (His) at 2 μg/mL can bind Vudalimab. The EC50 is 0.3927 μg/mL.   |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | PD-1 & CTLA-4 |
| Cas No. | 2329669-72-7 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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