Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptional activity of the YAP/TAZ-TEAD complex and demonstrating antitumor activity [1].
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Description | SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptional activity of the YAP/TAZ-TEAD complex and demonstrating antitumor activity [1]. |
Molecular Weight | 361.36 |
Formula | C19H18F3N3O |
CAS No. | 2766575-48-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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SWTX-143 2766575-48-6 Stem Cells YAP inhibitor inhibit