store at low temperature
store at -20°C
Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa, vitronectin and Mac-1 receptors.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 213.00 | |
5 mg | In stock | $ 563.00 | |
10 mg | In stock | $ 886.00 | |
25 mg | In stock | $ 1,330.00 | |
50 mg | In stock | $ 1,780.00 | |
100 mg | In stock | $ 2,430.00 |
Description | Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa, vitronectin and Mac-1 receptors. |
In vitro |
Inhibiting platelet aggregation induced by physiologic and pathologic agonists, abciximab (C7E3) achieves this effect by binding to the platelet αIIbβ3 integrin[2]. Abciximab appears to have similar affinity for the αIIbβ3 and αvβ3 integrins and redistributes between them[2]. |
In vivo | Effectively preventing neointimal hyperplasia, abciximab (C7E3) is administered at a dose of 0.25 mg/kg/day via intravenous infusion for 28 days[2]. |
Synonyms | C7E3 |
Molecular Weight | N/A |
CAS No. | 143653-53-6 |
store at low temperature
store at -20°C
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Abciximab 143653-53-6 Cytoskeletal Signaling Integrin C7E3 inhibitor inhibit