Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TM-1 is a potent pyruvate dehydrogenase kinase (PDHK) inhibitor that inhibits the activity of PDHK1 (IC50: 2.97 μM) and PDHK2 (IC50: 5.2 μM). TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation and inhibits cancer cell proliferation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | Inquiry | |
50 mg | 6-8 weeks | Inquiry | |
100 mg | 6-8 weeks | Inquiry |
Description | TM-1 is a potent pyruvate dehydrogenase kinase (PDHK) inhibitor that inhibits the activity of PDHK1 (IC50: 2.97 μM) and PDHK2 (IC50: 5.2 μM). TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation and inhibits cancer cell proliferation. |
Molecular Weight | 468.54 |
Formula | C26H32N2O6 |
CAS No. | 921099-13-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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TM-1 921099-13-0 inhibitor inhibit