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6,9-Dichloro-1,2,3,4-tetrahydroacridine

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Catalog No. T35975Cas No. 5396-25-8

6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids that possess radical scavenging, amyloid-β aggregation inhibitory, and/or β-secretase 1 (BACE1) inhibitory activities in addition to their activity as AChE inhibitors.2,3

6,9-Dichloro-1,2,3,4-tetrahydroacridine

6,9-Dichloro-1,2,3,4-tetrahydroacridine

😃Good
Catalog No. T35975Cas No. 5396-25-8
6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids that possess radical scavenging, amyloid-β aggregation inhibitory, and/or β-secretase 1 (BACE1) inhibitory activities in addition to their activity as AChE inhibitors.2,3
Pack SizePriceAvailabilityQuantity
25 mgTBD35 days
50 mgTBD35 days
100 mgTBD35 days
250 mgTBD35 days
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Product Introduction

Bioactivity
Description
6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids that possess radical scavenging, amyloid-β aggregation inhibitory, and/or β-secretase 1 (BACE1) inhibitory activities in addition to their activity as AChE inhibitors.2,3
Chemical Properties
Molecular Weight252.139
FormulaC13H11Cl2N
Cas No.5396-25-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 1 mg/mL (3.97 mM), Sonication is recommended.
DMF:PBS (pH 7.2) (1:2): 0.33 mg/mL (1.31 mM), Sonication is recommended.
DMF: 5 mg/mL (19.83 mM), Sonication is recommended.
Ethanol: 1 mg/mL (3.97 mM), Sonication is recommended.
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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

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