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Anti-CTHRC1 Antibody (9F430) (Synonyms: collagen triple helix repeat containing 1)
Catalog No. TMAY-03846 Copy Product Info
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Anti-CTHRC1 Antibody (9F430) is a Rabbit antibody targeting CTHRC1. Anti-CTHRC1 Antibody (9F430) can be used in ELISA.
Anti-CTHRC1 Antibody (9F430)
Copy Product Info🥰Excellent
Catalog No. TMAY-03846
Synonyms collagen triple helix repeat containing 1
Anti-CTHRC1 Antibody (9F430) is a Rabbit antibody targeting CTHRC1. Anti-CTHRC1 Antibody (9F430) can be used in ELISA.
Anti-CTHRC1 Antibody
(9F430)
(9F430)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-CTHRC1 Antibody (9F430) is a Rabbit antibody targeting CTHRC1. Anti-CTHRC1 Antibody (9F430) can be used in ELISA. |
| Synonyms | collagen triple helix repeat containing 1 |
| Ig Type | Rabbit IgG |
| Clone | 9F430 |
| Reactivity | Rat |
| Specificity | Rat CTHRC1 |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat CTHRC1 (rR CTHRC1; TMPY-04288; NP_001258229.1; Met1-Lys230). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Collagen triple helix repeat-containing protein 1, also known as Protein NMTC1, and CTHRC1, is a secreted protein that is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 expression was not detectable in normal arteries. However, it is transiently expressed in the arterial wall in response to injury where it may contribute to vascular remodeling by limiting collagen matrix deposition and promoting cell migration. A short collagen motif with 12 Gly-X-Y repeats appears to be responsible for trimerization of the CTHRC1 protein and this renders the molecule susceptible to cleavage by collagenase. CTHRC1 overexpression caused a dramatic reduction in collagen type I mRNA and protein levels. Currently available data indicate that Cthrc1 expression in vascular cells regulates transforming growth factor beta responsiveness, thereby impacting transforming growth factor beta target genes, including collagens. Additionally, CTHRC1 increases bone mass as a positive regulator of osteoblastic bone formation and offers an anabolic approach for the treatment of osteoporosis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Rat CTHRC1 Protein (TMPY-04288) |
| Antigen Species | Rat |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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