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1,2,3,6-Tetragalloylglucose

Name: 1,2,3,6-Tetragalloylglucose
Brand: TargetMol
SKU: TN1160
Price: 169 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN1160Cas No. 79886-50-3

Alias TeGG, 1,2,3,6-Tetra-O-galloyl-β-D-glucose

1,2,3,6-Tetragalloylglucose (TeGG) has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM).

1,2,3,6-Tetragalloylglucose

🥰Excellent

Purity: 99.52%

Catalog No. TN1160Alias TeGG, 1,2,3,6-Tetra-O-galloyl-β-D-glucoseCas No. 79886-50-3

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$169	In Stock	In Stock
5 mg	$428	-	In Stock
10 mg	$662	-	In Stock
25 mg	$987	-	In Stock
50 mg	$1,370	-	In Stock
1 mL x 10 mM (in DMSO)	$628	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.52%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	1,2,3,6-Tetragalloylglucose (TeGG) has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM).
Targets&IC50	UGT1A1:1.68 μM(Ki), Anticomplement activity:34 microM
In vitro	Two phenolics, 1,2,6-trigalloylglucose (1) and 1,2,3,6-Tetragalloylglucose (2), isolated from the stem-bark of Juglans mandshurica were evaluated for their antioxidative activities. The results showed that compounds 1 and 1,2,3,6-Tetragalloylglucose exhibited strong scavenging activities against 1,1'-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis-(3-ethylbenzenthiazoline-6-sulphonic) acid (ABTS(+)), and superoxide radicals (O(2)(-)), and also had a significant inhibitory effect on lipid peroxidation and low-density lipoprotein (LDL) oxidation[1]
Synonyms	TeGG, 1,2,3,6-Tetra-O-galloyl-β-D-glucose

Chemical Properties

Molecular Weight	788.57
Formula	C₃₄H₂₈O₂₂
Cas No.	79886-50-3
Smiles	O[C@@H]1[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H]1OC(=O)c1cc(O)c(O)c(O)c1
Relative Density.	2.02 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature,The compound is unstable in solution. Please use soon,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 91 mg/mL (115.4 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (4.18 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2681 mL	6.3406 mL	12.6812 mL	63.4059 mL
5 mM	0.2536 mL	1.2681 mL	2.5362 mL	12.6812 mL
10 mM	0.1268 mL	0.6341 mL	1.2681 mL	6.3406 mL
20 mM	0.0634 mL	0.3170 mL	0.6341 mL	3.1703 mL
50 mM	0.0254 mL	0.1268 mL	0.2536 mL	1.2681 mL
100 mM	0.0127 mL	0.0634 mL	0.1268 mL	0.6341 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc