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Synonyms: CDN1, Bcl-2-like protein 7, Bcl2-L-7, BCL2L7, Bcl-2 homologous antagonist/killer, BAK 1, BAK, Apoptosis regulator BAK
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
| Description | Anti-BAK1 Antibody (5Y66) is an antibody targeting BAK1. Anti-BAK1 Antibody (5Y66) can be used in ELISA,FCM,IHC,IP,WB. |
| Synonyms | CDN1, Bcl-2-like protein 7, Bcl2-L-7, BCL2L7, Bcl-2 homologous antagonist/killer, BAK 1, BAK, Apoptosis regulator BAK |
| Ig Type | Rabbit IgG |
| Clone | 5Y66 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200; IP:1:200-1:1000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Mitochondrion outer membrane; Single-pass membrane protein. |
| Tissue Specificity | Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human BAK1 |
| Antigen Species | Human |
| Gene Name | BAK1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cell Biology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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