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Anti-NDRG1 Antibody (5J128)
(Synonyms: TDD5, TARG1, RTP, RIT42, PROXY1, N-myc downstream regulated 1, NMSL, NDR1, HMSNL, GC4, DRG-1, DRG1, CMT4D, CAP43) Copy Product Info
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Synonyms: TDD5, TARG1, RTP, RIT42, PROXY1, N-myc downstream regulated 1, NMSL, NDR1, HMSNL, GC4, DRG-1, DRG1, CMT4D, CAP43
Catalog No. TMAH-00806 Copy Product Info
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Anti-NDRG1 Antibody (5J128) is an antibody targeting NDRG1. Anti-NDRG1 Antibody (5J128) can be used in ELISA,IF,IHC,WB.
Anti-NDRG1 Antibody
(5J128)
(5J128)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-NDRG1 Antibody (5J128) is an antibody targeting NDRG1. Anti-NDRG1 Antibody (5J128) can be used in ELISA,IF,IHC,WB. |
| Synonyms | TDD5, TARG1, RTP, RIT42, PROXY1, N-myc downstream regulated 1, NMSL, NDR1, HMSNL, GC4, DRG-1, DRG1, CMT4D, CAP43 |
| Ig Type | Rabbit IgG |
| Clone | 5J128 |
| Reactivity | Human, Mouse |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200; IF:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cell membrane. Note=Mainly cytoplasmic but differentially localized to other regions. Associates with the plasma membrane in intestinal epithelia and lactating mammary gland. Translocated to the nucleus in a p53/TP53-dependent manner. In prostate epithelium and placental chorion, located in both the cytoplasm and in the nucleus. No nuclear localization in colon epithelium cells. In intestinal mucosa, prostate and renal cortex, located predominantly adjacent to adherens junctions. Cytoplasmic with granular staining in proximal tubular cells of the kidney and salivary gland ducts. Recruits to the membrane of recycling/sorting and late endosomes via binding to phosphatidylinositol 4-phosphate. Associates with microtubules. Colocalizes with TUBG1 in the centrosome. Cytoplasmic location increased with hypoxia. Phosphorylated form found associated with centromeres during S-phase of mitosis and with the plasma membrane. |
| Tissue Specificity | Ubiquitous; expressed most prominently in placental membranes and prostate, kidney, small intestine, and ovary tissues. Also expressed in heart, brain, skeletal muscle, lung, liver and pancreas. Low levels in peripheral blood leukocytes and in tissues of |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Has a role in cell trafficking, notably of the Schwann cell, and is necessary for the maintenance and development of the peripheral nerve myelin sheath. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulates microtubule dynamics and maintains euploidy. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human NDRG1 |
| Antigen Species | Human |
| Gene Name | NDRG1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Neuroscience |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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