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Visugromab
(Synonyms: CTL-002, CTL002) Copy Product Info
🥰Excellent
Synonyms: CTL-002, CTL002
Catalog No. T80863 Copy Product Info
Purity: 95%
🥰Excellent
Visugromab (CTL-002) is a monoclonal antibody that targets and neutralises GDF-15. Visugromab exhibits synergistic anticancer activity with the anti-PD1 antibody Nivolumab, making it suitable for PD-1/PD-L1 recurrent/refractory metastatic solid tumours.
Visugromab
Cas No. 2556646-63-8
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | - | In Stock | |
| 5 mg | $647 | - | In Stock | |
| 10 mg | $987 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.8% (SDS-PAGE); 97.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Visugromab (CTL-002) is a monoclonal antibody that targets and neutralises GDF-15. Visugromab exhibits synergistic anticancer activity with the anti-PD1 antibody Nivolumab, making it suitable for PD-1/PD-L1 recurrent/refractory metastatic solid tumours. |
| In vivo | In preclinical toxicology studies on cynomolgus monkeys, Visugromab (maximum dose of 100 mg/kg, weekly) did not exhibit any signs of toxicity. [2] |
| Synonyms | CTL-002, CTL002 |
| Reactivity | Human |
| Verified Activity | Immobilized Human GDF-15 Protein (His) (TMPY-04727) at 1 μg/mL (100 μL/well) can bind Visugromab. The EC50 is 11.56 ng/mL. |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | GDF15/MIC1 |
| Molecular Weight | 144.50 kDa |
| Cas No. | 2556646-63-8 |
| Isotype | Human IgG4 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Visugromab in vivo | Visugromab molecular weight
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