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Visugromab

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Catalog No. T80863Cas No. 2556646-63-8
Alias CTL-002, CTL002

Visugromab (CTL-002) is a monoclonal antibody that targets and neutralises GDF-15. Visugromab exhibits synergistic anticancer activity with the anti-PD1 antibody Nivolumab, making it suitable for PD-1/PD-L1 recurrent/refractory metastatic solid tumours.

Visugromab

Visugromab

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Purity: 95%
Catalog No. T80863Alias CTL-002, CTL002Cas No. 2556646-63-8
Visugromab (CTL-002) is a monoclonal antibody that targets and neutralises GDF-15. Visugromab exhibits synergistic anticancer activity with the anti-PD1 antibody Nivolumab, making it suitable for PD-1/PD-L1 recurrent/refractory metastatic solid tumours.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$247-In Stock
5 mg$647-In Stock
10 mg$987-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.8% (SDS-PAGE); 97.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Visugromab (CTL-002) is a monoclonal antibody that targets and neutralises GDF-15. Visugromab exhibits synergistic anticancer activity with the anti-PD1 antibody Nivolumab, making it suitable for PD-1/PD-L1 recurrent/refractory metastatic solid tumours.
In vivo
In preclinical toxicology studies on cynomolgus monkeys, Visugromab (maximum dose of 100 mg/kg, weekly) did not exhibit any signs of toxicity. [2]
SynonymsCTL-002, CTL002
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetGDF15/MIC1
Chemical Properties
Molecular Weight144.50 kDa
Cas No.2556646-63-8
Antibody Information
IsotypeHuman IgG4 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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