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HSGN-218 is a gut-restrictive antibiotic.1It is active againstC. difficile(MIC = 0.007 μg/ml) and clinical isolates ofC. difficile(MICs = 0.003-0.03 μg/ml) and is not cytotoxic to Caco-2 cells when used at concentrations ranging from 4 to 64 μg/ml. HSGN-218 (50 mg/kg) increases survival and protects mice fromC. difficilerecurrence in mouse models ofC. difficileinfection.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $87 | Backorder | |
5 mg | $404 | Backorder | |
10 mg | $677 | Backorder | |
25 mg | $1,471 | Backorder |
Description | HSGN-218 is a gut-restrictive antibiotic.1It is active againstC. difficile(MIC = 0.007 μg/ml) and clinical isolates ofC. difficile(MICs = 0.003-0.03 μg/ml) and is not cytotoxic to Caco-2 cells when used at concentrations ranging from 4 to 64 μg/ml. HSGN-218 (50 mg/kg) increases survival and protects mice fromC. difficilerecurrence in mouse models ofC. difficileinfection. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO:PBS (pH 7.2) (1:3): 0.25 mg/mL, Sonication is recommended. DMF: 30 mg/mL, Sonication is recommended. Ethanol: 1 mg/mL, Sonication is recommended. DMSO: 30 mg/mL, Sonication is recommended. |
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