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Urocortin, human
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Catalog No. TP1021Cas No. 176591-49-4
Alias Urocortin (human), Human urocortin I, Human urocortin 1, Human urocortin
Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF).
Urocortin, human
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Purity: 99.26%
Catalog No. TP1021Alias Urocortin (human), Human urocortin I, Human urocortin 1, Human urocortinCas No. 176591-49-4
Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 500 μg | $98 | Inquiry | Inquiry | |
| 1 mg | $163 | Inquiry | Inquiry | |
| 5 mg | $372 | Inquiry | Inquiry | |
| 10 mg | $548 | Inquiry | Inquiry | |
| 25 mg | $869 | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.26%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF). |
| Targets&IC50 | CRF2β (mouse): 0.5 nM, CRF1 (human):0.4nM, CRF2α (rat):0.3 nM |
| In vitro | Urocortin, human, is a selective agonist of the CRF2 receptor, displaying Ki values of 0.4 nM for human CRF1, 0.3 nM for rat CRF2α, and 0.5 nM for mouse CRF2β receptors in cell assays [1]. |
| In vivo | Urocortin (0.01 to 10 μg) decreases food intake in both food-deprived and non-deprived rats, with similar effects observed in mice following a 1 μg i.c.v. administration. It is a potent suppressor of ingestive behavior and has the potential to induce anxiogenic behavior[2]. |
| Synonyms | Urocortin (human), Human urocortin I, Human urocortin 1, Human urocortin |
| Molecular Weight | 4696.32 |
| Formula | C204H337N63O64 |
| Cas No. | 176591-49-4 |
| Relative Density. | no data available |
| Sequence | Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2 |
| Sequence Short | DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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