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Bromfenac Sodium

Name: Bromfenac Sodium
Brand: TargetMol
SKU: T6424
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T6424Cas No. 91714-93-1

Alias Bronuck, AHR 10282R, AHR 10282B

Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.

Bromfenac Sodium

🥰Excellent

Purity: 99.93%

Catalog No. T6424Alias Bronuck, AHR 10282R, AHR 10282BCas No. 91714-93-1

Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.

Pack Size	Price	Availability
10 mg	$30	In Stock
25 mg	$45	In Stock
50 mg	$58	In Stock
100 mg	$73	In Stock
500 mg	$178	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.93%

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COA HPLC HNMR LCMS

Product Introduction

Bioactivity

Description	Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.
Targets&IC50	COX-1:5.56 nM (IC50), COX-2:7.45 nM (IC50)
Synonyms	Bronuck, AHR 10282R, AHR 10282B

Chemical Properties

Molecular Weight	356.15
Formula	C₁₅H₁₁BrNO₃·Na
Cas No.	91714-93-1
Smiles	[Na+].NC1=C(C=CC=C1CC([O-])=O)C(=O)C1=CC=C(Br)C=C1
Relative Density.	no data available
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 65 mg/mL (182.51 mM), Sonication is recommended.

Ethanol: 2 mg/mL (5.62 mM), Sonication is recommended.

DMSO: 55 mg/mL (154.43 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (2.81 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	2.8078 mL	14.0390 mL	28.0781 mL	140.3903 mL
5 mM	0.5616 mL	2.8078 mL	5.6156 mL	28.0781 mL

DMSO/H2O

	1mg	5mg	10mg	50mg
10 mM	0.2808 mL	1.4039 mL	2.8078 mL	14.0390 mL
20 mM	0.1404 mL	0.7020 mL	1.4039 mL	7.0195 mL
50 mM	0.0562 mL	0.2808 mL	0.5616 mL	2.8078 mL
100 mM	0.0281 mL	0.1404 mL	0.2808 mL	1.4039 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc