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Ginsenoside F3

Name: Ginsenoside F3
Brand: TargetMol
SKU: T3829
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3829Cas No. 62025-50-7

Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in murine spleen cells (10 μM).

Ginsenoside F3

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Purity: 99.95%

Catalog No. T3829Cas No. 62025-50-7

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$36	In Stock	In Stock
5 mg	$77	In Stock	In Stock
10 mg	$110	In Stock	In Stock
25 mg	$179	In Stock	In Stock
50 mg	$266	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.95%

Color:White

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COA LCMS HNMR

Product Introduction

Ginsenoside F3 AI Summary

Ginsenoside F3 shows no significant inhibition of human DNA topoisomerase 1 or 2-mediated relaxation of supercoiled DNA, with IC50 values exceeding 250,000 nM in both assays. However, the compound exhibits inhibitory bioactivity against cell proliferation, demonstrated by the sulforhodamine B assay results. At a concentration of 100 µM after 72 hours, Ginsenoside F3 shows 103.91% activity in human U251 cells and 93.57% activity in rat C6 cells, indicating potential anti-proliferative effects on these cell lines..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Chemical Properties

Molecular Weight	770.99
Formula	C₄₁H₇₀O₁₃
Cas No.	62025-50-7
Smiles	[H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])[C@@H](O)C[C@@]21C)[C@](C)(CCC=C(C)C)O[C@@H]1O[C@H](CO[C@@H]2OC[C@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O
Relative Density.	1.31 g/cm3 at 20℃

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: Soluble

Pyridine, Methanol, etc.: Soluble

DMSO: 250 mg/mL (324.26 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (2.59 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2970 mL	6.4852 mL	12.9703 mL	64.8517 mL
5 mM	0.2594 mL	1.2970 mL	2.5941 mL	12.9703 mL
10 mM	0.1297 mL	0.6485 mL	1.2970 mL	6.4852 mL
20 mM	0.0649 mL	0.3243 mL	0.6485 mL	3.2426 mL
50 mM	0.0259 mL	0.1297 mL	0.2594 mL	1.2970 mL
100 mM	0.0130 mL	0.0649 mL	0.1297 mL	0.6485 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc